| November 16, 2042 | HIGH POINT PANTHERS | L 77-81 | 0-1 | S. Crockett 19 | S. Crockett 4 | J. Hester 7 |
| November 19, 2042 | @ Temple Owls | W 78-67 | 1-1 | S. Crockett 16 | N. Lyall 5 | N. Lyall 6 |
| November 21, 2042 | @ St. Bonaventure Bonnies Hall of Fame Classic | W 75-72 | 2-1 | V. Winter 13 | S. Crockett 5 | V. Winter 7 |
| November 22, 2042 | @ #11 West Virginia Mountaineers Hall of Fame Classic | L 77-86 | 2-2 | K. Lewandowski 16 | S. Crockett 3 | S. Crockett 5 |
| November 26, 2042 | SAN DIEGO STATE AZTECS | L 70-84 | 2-3 | S. Crockett 16 | J. Hester 4 | J. Hester 3 |
| November 29, 2042 | @ Kentucky Wildcats | L 61-76 | 2-4 | S. Crockett 10 | K. Lewandowski 4 | J. Hester 8 |
| December 3, 2042 | @ Fordham Rams | L 74-90 | 2-5 | T. Stock 17 | S. Crockett 3 | D. Pruitt 4 |
| December 7, 2042 | FRESNO STATE BULLDOGS | L 76-100 | 2-6 | S. Phillips 17 | F. Collins 5 | N. Lyall 5 |
| December 13, 2042 | @ Davidson Wildcats | W 89-59 | 3-6 | S. Crockett 19 | S. Crockett 6 | J. Hester 8 |
| December 20, 2042 | @ Missouri Tigers | L 64-86 | 3-7 | V. Winter 13 | S. Crockett 5 | J. Hester 7 |
| December 26, 2042 | @ California Golden Bears (1-8, 0-0, 1-4 Home)* | - | | | | |
| December 28, 2042 | @ Stanford Cardinal (11-1, 0-0, 6-0 Home)* | - | | | | |
| January 2, 2043 | LOUISVILLE CARDINALS (9-2, 0-0, 3-0 Away)* | - | | | | |
| January 4, 2043 | FLORIDA STATE SEMINOLES (7-2, 0-0, 0-2 Away)* | - | | | | |
| January 9, 2043 | NC STATE WOLFPACK (6-3, 0-0, 0-2 Away)* | - | | | | |
| January 11, 2043 | CLEMSON TIGERS (2-7, 0-0, 1-3 Away)* | - | | | | |
| January 16, 2043 | @ SMU Mustangs (6-4, 0-0, 5-2 Home)* | - | | | | |
| January 18, 2043 | BOSTON COLLEGE EAGLES (3-6, 0-0, 1-2 Away)* | - | | | | |
| January 23, 2043 | DUKE BLUE DEVILS (5-4, 0-0, 1-2 Away)* | - | | | | |
| January 25, 2043 | VIRGINIA CAVALIERS (2-7, 0-0, 1-4 Away)* | - | | | | |
| January 30, 2043 | @ Syracuse Orange (6-3, 0-0, 5-1 Home)* | - | | | | |
| February 1, 2043 | @ Miami (FL) Hurricanes (9-2, 0-0, 5-0 Home)* | - | | | | |
| February 6, 2043 | NOTRE DAME FIGHTING IRISH (8-4, 0-0, 0-3 Away)* | - | | | | |
| February 8, 2043 | @ North Carolina Tar Heels (10-1, 0-0, 5-0 Home)* | - | | | | |
| February 13, 2043 | @ Virginia Tech Hokies (4-6, 0-0, 3-3 Home)* | - | | | | |
| February 15, 2043 | PITTSBURGH PANTHERS (7-4, 0-0, 0-3 Away)* | - | | | | |
| February 20, 2043 | GEORGIA TECH YELLOW JACKETS (8-3, 0-0, 2-2 Away)* | - | | | | |
| February 22, 2043 | @ Pittsburgh Panthers (7-4, 0-0, 4-1 Home)* | - | | | | |
| February 27, 2043 | @ Virginia Cavaliers (2-7, 0-0, 1-2 Home)* | - | | | | |
| March 1, 2043 | @ Florida State Seminoles (7-2, 0-0, 7-0 Home)* | - | | | | |
