| November 16, 2042 | @ #11 Florida State Seminoles | L 48-68 | 0-1 | D. Sousa 11 | P. Winter 3 | D. Sousa 6 |
| November 17, 2042 | WASHINGTON STATE COUGARS | W 70-51 | 1-1 | J. Rose 23 | P. Winter 5 | T. King 10 |
| November 21, 2042 | MIDDLE TENNESSEE BLUE RAIDERS | L 51-61 | 1-2 | J. Rose 13 | P. Winter 3 | J. Rose 8 |
| November 30, 2042 | LAMAR CARDINALS | W 80-62 | 2-2 | J. Rose 31 | P. Winter 5 | P. Winter 7 |
| December 7, 2042 | ARMY BLACK KNIGHTS | L 66-67 | 2-3 | J. Rose 17 | D. Rolle 4 | J. Rose 8 |
| December 9, 2042 | MISSOURI STATE BEARS Baha Mar Hoops Bahamas Championship | L 74-90 | 2-4 | J. Rose 15 | P. Winter 6 | D. Sousa 10 |
| December 13, 2042 | MARQUETTE GOLDEN EAGLES | W 83-76 | 3-4 | P. Winter 21 | J. Rose 7 | A. Riley 6 |
| December 17, 2042 | UC IRVINE ANTEATERS | W 70-52 | 4-4 | J. Rose 17 | P. Winter 3 | D. Sousa 10 |
| December 21, 2042 | BROWN BEARS | W 71-68 | 5-4 | A. Riley 13 | D. Rolle 4 | T. King 7 |
| December 26, 2042 | @ #6 Minnesota Golden Gophers* | L 40-87 | 5-5 | J. Rose 10 | T. King 2 | J. Rose 7 |
| December 28, 2042 | @ Michigan Wolverines* | L 70-90 | 5-6 | A. Riley 17 | J. Rose 4 | T. King 7 |
| January 2, 2043 | UCLA BRUINS* | W 82-54 | 6-6 | P. Winter 17 | J. Rose 4 | D. Sousa 9 |
| January 4, 2043 | @ Indiana Hoosiers* | L 57-73 | 6-7 | P. Winter 20 | P. Winter 3 | J. Barnard 7 |
| January 9, 2043 | MICHIGAN STATE SPARTANS* | W 71-67 | 7-7 | J. Rose 20 | P. Winter 8 | T. King 9 |
| January 11, 2043 | @ Oregon Ducks* | L 65-88 | 7-8 | J. Rose 19 | P. Winter 5 | J. Rose 7 |
| January 16, 2043 | NEBRASKA CORNHUSKERS* | W 85-81 | 8-8 | A. Riley 23 | D. Sousa 3 | P. Winter 5 |
| January 18, 2043 | @ #16 Iowa Hawkeyes* | L 66-82 | 8-9 | J. Rose 20 | P. Winter 3 | D. Sousa 6 |
| January 23, 2043 | RUTGERS SCARLET KNIGHTS* | W 57-55 | 9-9 | P. Winter 23 | J. Rose 4 | J. Rose 10 |
| January 25, 2043 | OHIO STATE BUCKEYES* | W 77-63 | 10-9 | J. Rose 16 | P. Winter 6 | T. King 8 |
| January 30, 2043 | @ USC Trojans* | L 53-83 | 10-10 | J. Rose 15 | P. Winter 3 | J. Rose 7 |
| February 1, 2043 | WASHINGTON HUSKIES* | W 71-63 | 11-10 | P. Winter 15 | T. King 6 | T. King 6 |
| February 6, 2043 | #14 MARYLAND TERRAPINS* | L 80-83 | 11-11 | D. Sousa 23 | P. Winter 6 | D. Sousa 9 |
| February 8, 2043 | @ Illinois Fighting Illini* | L 63-81 | 11-12 | J. Rose 15 | J. Rose 3 | D. Sousa 6 |
| February 13, 2043 | PENN STATE NITTANY LIONS (18-5, 12-2, 8-3 Away)* | - | | | | |
| February 15, 2043 | @ Purdue Boilermakers (18-7, 8-6, 12-2 Home)* | - | | | | |
| February 20, 2043 | NORTHWESTERN WILDCATS (12-13, 7-7, 4-6 Away)* | - | | | | |
| February 22, 2043 | ILLINOIS FIGHTING ILLINI (16-7, 9-5, 4-6 Away)* | - | | | | |
| February 27, 2043 | @ Penn State Nittany Lions (18-5, 12-2, 10-1 Home)* | - | | | | |
| March 1, 2043 | @ UCLA Bruins (9-15, 4-10, 7-7 Home)* | - | | | | |
