| November 16, 2042 | @ #11 Florida State Seminoles | L 48-68 | 0-1 | D. Sousa 11 | P. Winter 3 | D. Sousa 6 |
| November 17, 2042 | WASHINGTON STATE COUGARS | W 70-51 | 1-1 | J. Rose 23 | P. Winter 5 | T. King 10 |
| November 21, 2042 | MIDDLE TENNESSEE BLUE RAIDERS | L 51-61 | 1-2 | J. Rose 13 | P. Winter 3 | J. Rose 8 |
| November 30, 2042 | LAMAR CARDINALS | W 80-62 | 2-2 | J. Rose 31 | P. Winter 5 | P. Winter 7 |
| December 7, 2042 | ARMY BLACK KNIGHTS | L 66-67 | 2-3 | J. Rose 17 | D. Rolle 4 | J. Rose 8 |
| December 9, 2042 | MISSOURI STATE BEARS Baha Mar Hoops Bahamas Championship | L 74-90 | 2-4 | J. Rose 15 | P. Winter 6 | D. Sousa 10 |
| December 13, 2042 | MARQUETTE GOLDEN EAGLES | W 83-76 | 3-4 | P. Winter 21 | J. Rose 7 | A. Riley 6 |
| December 17, 2042 | UC IRVINE ANTEATERS | W 70-52 | 4-4 | J. Rose 17 | P. Winter 3 | D. Sousa 10 |
| December 21, 2042 | BROWN BEARS | W 71-68 | 5-4 | A. Riley 13 | D. Rolle 4 | T. King 7 |
| December 26, 2042 | @ Minnesota Golden Gophers (9-2, 0-0, 5-1 Home)* | - | | | | |
| December 28, 2042 | @ Michigan Wolverines (4-5, 0-0, 4-2 Home)* | - | | | | |
| January 2, 2043 | UCLA BRUINS (5-5, 0-0, 0-1 Away)* | - | | | | |
| January 4, 2043 | @ Indiana Hoosiers (7-4, 0-0, 3-1 Home)* | - | | | | |
| January 9, 2043 | MICHIGAN STATE SPARTANS (7-3, 0-0, 1-3 Away)* | - | | | | |
| January 11, 2043 | @ Oregon Ducks (4-5, 0-0, 4-2 Home)* | - | | | | |
| January 16, 2043 | NEBRASKA CORNHUSKERS (3-6, 0-0, 0-2 Away)* | - | | | | |
| January 18, 2043 | @ Iowa Hawkeyes (9-1, 0-0, 4-0 Home)* | - | | | | |
| January 23, 2043 | RUTGERS SCARLET KNIGHTS (8-1, 0-0, 0-0 Away)* | - | | | | |
| January 25, 2043 | OHIO STATE BUCKEYES (4-5, 0-0, 0-1 Away)* | - | | | | |
| January 30, 2043 | @ USC Trojans (8-2, 0-0, 6-0 Home)* | - | | | | |
| February 1, 2043 | WASHINGTON HUSKIES (3-6, 0-0, 0-3 Away)* | - | | | | |
| February 6, 2043 | MARYLAND TERRAPINS (7-3, 0-0, 1-2 Away)* | - | | | | |
| February 8, 2043 | @ Illinois Fighting Illini (7-2, 0-0, 5-0 Home)* | - | | | | |
| February 13, 2043 | PENN STATE NITTANY LIONS (6-3, 0-0, 1-2 Away)* | - | | | | |
| February 15, 2043 | @ Purdue Boilermakers (10-1, 0-0, 7-1 Home)* | - | | | | |
| February 20, 2043 | NORTHWESTERN WILDCATS (5-6, 0-0, 1-2 Away)* | - | | | | |
| February 22, 2043 | ILLINOIS FIGHTING ILLINI (7-2, 0-0, 2-2 Away)* | - | | | | |
| February 27, 2043 | @ Penn State Nittany Lions (6-3, 0-0, 5-0 Home)* | - | | | | |
| March 1, 2043 | @ UCLA Bruins (5-5, 0-0, 4-3 Home)* | - | | | | |
